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Dr. Max He is Vice President of Medical Informatics at Simcere Diagnostics Co.,
Ltd. Before joining the Simcere Diagnostics, he was a tenure-track faculty member at
the rank of Assistant Professor in the Center for Human Genetics at Marshfield Clinic
Research Foundation (MCRF). He also held a joint appointment in the Biomedical
Informatics Research Center at MCRF and an adjunct Professorship in the Computation
and Informatics in Biology and Medicine (CIBM) at University of Wisconsin-Madison.
Prior to assuming his tenure-track faculty position, Dr. He served as Assistant Professor
in the Center for Human Genome Variation at Duke University School of Medicine with
responsibilities including leading development of a number of statistical methods for
analyzing over 4,000 whole genome/exome sequencing data for a number of studies.
The current focus of Dr. He’s department is on developing statistical methods, machine
learning approaches, and computational tools for genomic medicine and clinical
diagnostics. Several Big Data based toolsets developed by him and his team have
shown practical applications in which genetic diagnosis can potentially be applied in
clinical diagnosis and/or personalized treatment by the discovery of clinically actionable
genetic variants.
Dr. He was invited to present his studies at the American Society of Human
Genetics (ASHG) 2015 Annual Meeting and the American College of Medical Genetics
and Genomics (ACMG) 2016 Annual Meeting. His research has been published in
multiple high impact scientific journals and has been reported by American media for
several times
Current Research
Developing Big Data based statistical methods and tools for analyzing large-scale
high-throughput sequencing data
Discovering genetic biomarkers for diagnosing and/or monitoring treatment
effectiveness in colorectal cancer
Rapidly determination of bacterial and viral compositions for clinical usage
Interested topics
Cancer Genetics
Bioinformatics in Genomics and Genome Technology
Clinical Genetic Testing
Pharmacogenetics
Prenatal, Perinatal and Reproductive Genetics
Epigenetics
Evolutionary and Population Genetics
Genome Structure, Variation, and Function
Microbial Genomics
Statistical Genetics and Genetic Epidemiology
Psychiatric Genetics, Neurogenetics, and Neurodegeneration
Complex Traits and Polygenic Disorders
2011 – Scientific Committee, Critical Assessment of Massive Data Analysis
(CAMDA)
2011 – Faculty Appointment, School of Medicine at Duke University, USA
2012 – Faculty Appointment, Center for Human Genetics & Biomedical
Informatics Research Center at Marshfield Clinic Research Foundation, USA
2013 – Faculty Appointment, Computation, and Informatics in Biology and
Medicine at University of Wisconsin-Madison, USA
2017 – Scientific Grant Reviewer, Department for Economy, Science and
Transport, Welsh Government of the United Kingdom
Scientific Research with Dr. Kai Wang at Columbia University, USA
Scientific Research with Dr. Song Liu at Roswell Park Cancer Institute, USA
Peer-Review Activities
PLoS Genetics
Oncotarget
Biostatistics
BMC Bioinformatics
BMC Complementary and Alternative Medicine
Frontiers in Genetics
Journal of Chemical Information and Computer Sciences
Member of Editorial Board
International Journal of Advanced Bioinformatics
Membership
The American Society of Human Genetics
The American Medical Informatics Association
International Society of Biocuration
Conference Organization
Session Chair, Critical Assessment of Massive Data Analysis (CAMDA) (2011)