Dr. Sherry Dadgar is an Assistant Professor of Medicine at The George Washington University. She has a B.S. degree in Cellular Molecular Biology (Genetics), M.S. in Bioinformatics and M.Phil.in Biomedical Sciences. Dr. Dadgar earned her Ph.D. in Molecular Medicine at the George Washington University, School of Medicine & Health Sciences and pursued post-doctoral training at the Center for Genetic Medicine, Children’s National Health System in DC. She completed her fellowship training in Clinical Molecular Genetics at National Human Genome Research Institute (NHGRI), National Institute of Health (NIH). Dr. Dadgar is awarded multiple research grants from Muscular Dystrophy Association (MDA), Children’s National Medical Center’s Board of Visitors and other institutions to support her scientific work on genetic disorders. She is the recipient of MDA research award for identifying a novel molecular mechanism of pathogenesis in Duchenne Muscular Dystrophy. Dr. Dadgar is the author of several scientific papers on several genetic disorders published in peer-reviewed journals. She has served as a scientific reviewer and editorial board member in several scientific journals. Dr.Dadgar is also serving as a committee member of American Clinical Laboratory Association (ACLA) to address legislative and ethical issues. Her ultimate career goal is to improve patient care using personalized medicine approaches.
Education:
Fellowship-Clinical Molecular Genetics; NIH, NHGRI, 2015
Ph.D.-Molecular Medicine (Genetics); George Washington University, 2013
M.Phil.-Biomedical Sciences; George Washington University, 2013
M.Sc.-Bioinformatics; Rochester Institute of Technology, 2008
B.Sc.-Cellular and Molecular Biology; Azad Tehran University, 2000
Scientific Awards and Honors
2013- Muscular Dystrophy Association (MDA) International Annual Meeting research award for identifying a novel mechanisms of pathogenesis in Duchenne Muscular Dystrophy
2012- George Washington University Research Award on Ph.D. Thesis Project
2009-2013- Graduate Scholarship, George Washington University
2006-2008- Graduate Merit Scholarship (with an increment in the second year based on academic
performance), Rochester Institute of Technology
2004- Literary award for the book titled “The Prosody of Modern Poem”, Tehran
Research Grant Awards and Honors
2012- 2013- Board of Visitor Grant Award, Children’s National Medical Ctr. (PI)
2012-2015- Muscular Dystrophy Association (MDA) Grant Award, USA (Co-PI)
2013- U.S. Army Medical Research and Materiel Command Grant Award (Co-PI)
Professional Memberships
Current Member, American College of Medical Genetics
Current Member, American Society of Human Genetics
2013 Member, Muscular Dystrophy Association
2008 Member, International Society for Computational Biology
Publications
1. Many GM, Yokosaki Y, Uaesoontrachoon K, Nghiem PP, Bello L, Dadgar S, Yin Y,Damsker JM, Cohen HB, Kornegay JN, Bamman MM, Mosser DM, Nagaraju K, Hoffman EP. OPN-a induces muscle inflammation by increasing recruitment and activation of pro-inflammatory Macrophages. Exp Physiol. 2016 Oct 1;101(10):1285-1300. doi: 10.1113/EP085768. PubMed PMID: 27452303.
2. Dadgar S, Wang Z, Johnston H, Kesari A, Nagaraju K, Chen YW, Hill DA, Partridge TA, Giri M, Freishtat RJ, Nazarian J, Xuan J, Wang Y, Hoffman EP. Asynchronous remodeling is a driver of failed regeneration in Duchenne muscular dystrophy. J Cell Biol. 2014 Oct 13;207(1):139-58. doi: 10.1083/jcb.201402079.
3. Heier C.R., Damsker J.M., YuQ, Dillingham B.C., Huynh T, Van der Meulen J.H. , Sali A, Miller B.K., Phadke A, Scheffer L, QuinnL, Tatem K, Jordan S, Dadgar S, Rodriguez O.C., Chris Albanese C, CalhounM, Gordish H, Jaiswal J.K., Connor E.M., McCall J.M., Hoffman E.P., Reeves E.K., Nagaraju
Sherry Dadgar sherry.dadgar@gmail.com
K, VBP15, a novel anti-inflammatory and membrane-stabilizer, improves muscular dystrophy. EMBO Mol Med. 2013 Oct;5(10):1569-85. doi: 10.1002/emmm.201302621. PubMed PMID: 24014378
4. Duguez S, Duddy WJ, Gnocchi V, Bowe J, Dadgar S, Partridge TA. Atmospheric Oxygen Tension Slows Myoblast Proliferation via Mitochondrial Activation. PLoSOne. 2012;7(8):e43853. Epub 2012 Aug
24. PubMed PMID: 22937109; PubMed Central
PMCID: PMC3427224.
5. Nazarian J, Berry DL, Sanjari S, Razvi M, Brown K, Hathout Y, Vertes A, Dadgar S, Hoffman EP. Evolution and comparative genomics of subcellular specializations: EST sequencing of Torpedo electric organ. Mar Genomics. 2011 Mar;4(1):33-40. Epub, 2011 Feb 12. PubMed PMID: 21429463; PubMed
Central PMCID: PMC3412124.
6. Reed B, Nobakht E, Dadgar S, Bekheirnia MR, Masoumi A, Belibi F, Yan XD, Cadnapaphornchai M, Schrier RW. Renal ultrasonographic evaluation in children at risk of autosomal dominant polycystic kidney disease. Am J Kidney Dis. 2010 Jul;56(1):50-6. Epub 2010 May 8. PubMed PMID: 20452711.
7. Easley R, Van Duyne R, Coley W, Guendel I, Dadgar S, Kehn-Hall K, KashanchiF.Chromatin dynamics associated with HIV-1 Tat-activated transcription. BiochimBiophysActa. 2010 Mar-Apr;1799(3-4):275-85. Epub 2009 Aug 27. Review. PubMed PMID: 19716452; PubMed Central PMCID: PMC2838975.
8. Dadgar S, Estimating Evolutionary Dynamics of Cleavage Site Peptides among H5HA Avian Influenza
Employing Mathematical Information Theory Approaches. Rochester Institute of Technology Publisher,
2008.
9. Moghaddam SJ, Haghighi EN, Samiee S, Shahid N, Keramati AR, Dadgar S, Zali MR. Immunohistochemical analysis of p53, cyclinD1, RB1, c-fos and N-ras gene expression in hepatocellular carcinoma in Iran. World J Gastroenterol. 2007 Jan 28;13(4):588-93. PubMed PMID: 17278226.
10. Dadgar S, Hagens O, Dadgar SR, Haghighi EN, Schimpf S, Wissinger B, Garshasbi M. Structural model of the OPA1 GTPase domain may explain the molecular consequences of a novel mutation in a family with autosomal dominant optic atrophy. Exp Eye Res. 2006 Sep;83(3):702-6. Epub 2006 May 12. PubMed PMID:16698014.
11. Dadgar S, Hafizi L, Kariminejad R, Ohadi M. Highly Sensitive Conventional PCR Testing of Free Fetal DNA in Maternal Serum for Non – Invasive Fetal Sex Determination. The Genetics in the 3rd Millennium 2005;20:123-9.
12. Garshasbi M, Dadgar S, Law H.Y, Neishabury M, Oberkanins C, Krugluger W, H.Najmabadi. The Spectrum of Alpha -Thalassemia Mutation in Iran, The Genetics In the 3rdMillennium 2003;12:256-62.
13. Dadgar S.R, Badakhsh MH, Amini A, Dadgar S. Screening of Fetal Chromosomal Abnormalities, The Medical Journal of the Islamic Republic of Iran 2003;17(3):127-35.