International Journal of Immunology is a peer-reviewed open access journal that publishes original research articles as well as review articles in all areas of immunology. Immunology is a diverse and growing discipline that can be defined as the study of the tissues, cells and molecules involved in host defense mechanisms. Immunologists attempt to understand how the immune system develops, how the body defends itself against disease, and what happens when it all goes wrong. Priority is given to work that provides fundamental insight into the workings of the immune system. Areas covered include, but are not limited to, innate immunity and inflammation; development; immune receptors, signaling and apoptosis; antigen presentation; gene regulation and recombination; cellular and systemic immunity; vaccines; immune tolerance; autoimmunity and tumor immunology, microbial immunopathology; and transplantation.
The great advances in immunology in recent years make this field one of the most dynamic and rapidly growing in biological sciences. This remarkable growth is stimulated by the influx of investigators from other disciplines such as biochemistry, genetics, molecular biology, microbiology, virology and various medical disciplines. These disciplines are so well interlinked with immunology that no immunological challenge can now be properly addressed without sophisticated applications of expertise of combinations of these disciplines. As a consequence, immunology has become a vast and rich field encompassing discoveries and outlooks that range from the highly clinical to the highly molecular. Although such perspectives may appear diverse, they are, in fact, extremely interdependent. The journal seeks to present a balanced overview of contemporary immunology and melds together different aspects of molecular immunology, immunobiology and clinical immunology.
Immunology is the branch of biomedical science that deals with the response of an organism to antigenic challenge and its recognition of what is self and what is not. It deals with the defense mechanisms including all physical, chemical and biological properties of the organism that help it to combat its susceptibility to foreign organisms, material, etc
Immunology has its origins in the study of how the body protects itself against infectious diseases caused by microorganisms, such as bacteria, viruses, protozoa, and fungi, and also parasitic organisms, such as helminth worms. Research / review articles deals with, among other things, the physiological functioning of the immune system in states of both health and disease; malfunctions of the immune system in immunological disorders (autoimmune diseases, hypersensitivities, immune deficiency, transplant rejection); the physical, chemical and physiological characteristics of the components of the immune system in vitro, in situ, and in vivo are of prime interest.
We take great pleasure in welcoming you to our new journal, International Journal of Immunology. We have created this publication with the intention of providing a space for the generation of knowledge, dialogue, critique, debate, and collaboration among an international community of immunologists, pathologists, researchers, scholars, etc.
Our vision is to create a high-quality publication that will be relevant, challenging, thought-provoking, for graduate students, academic researchers and scholars. We welcome original research papers, reviews articles, case studies, book reviews, and works-in progress.
We look forward to welcoming your submissions.
1. Adaptive immunity 11. Cancer and Tumor Immunobiology
2. Immunologic Techniques 12. Cellular & Regional Immunology
3. Transplantation Immunology 13. Combining Cancer Immunotherapies
4. Computational Immunology 14. Allergy prevention and risk factors
5. Immunology 15. Nutritional Immunology
6. Immunotherapy 16. Clinical Immunology
7. Pediatric Immunology 17. Reproductive Immunology
8. Immune Tolerance 18. Fungal Immunology
9. Mucosal Immunology 19. Neuro Immunology
10. Immune Toxicology 20.Immunoinformatics and System
Immune Scientific Networks:
Immunology Leadership & Committees consider proposals for Special Issues Editors will return a decision on your proposal within Two weeks of receipt. To enrich our vision of making the scientific information available at an ease of access, Immunology Leadership & Committees initiated special issue for the open access journals. All the articles published under a special issue focuses on a single topic providing the complete information about the ongoing research providing more insight on an emphasized topic of research enabling the readers access wide forecasted information on a particular topic Issue.
Special Issue Proposals: Special Issue deals with focused research topics of high interest, falling under the scope of the Journal. Special Issues are the pool of articles under a current topic selected from the Ongoing Research under specific discipline. The aim of the Special Issue is to provide a platform for the researchers to understand the recent advancements and challenges in particular areas of research. These articles will provide an opportunity to the readers to understand and access the scientific information.
We encourage potential scientists to organize the Special Issue in their field of interests that fits within the Journal scope. This will provide an opportunity to increase the visibility of the Guest Editors. The Special Issue Titles may be from any basic and clinical area of Science, Technology and Medicine. People interested in publishing a special issue are advised to consider the following guidelines.
Your proposal should contain:
By submitting a Special Issue proposal to Immunology Leadership & Committees, you agree to abide by the Special Issue Editor Protocol should your proposal be accepted
Special issue articles are published immediately upon their acceptance and are released under upcoming regular issues. Special Issues are invited throughout the year. For more information or any queries about the special issues, please write us to specialissues@helicsgroup.net or info@helicsgroup.net
Promoting Your Special Issue
Immunology Leadership & Committees will work with Guest Editors to increase the visibility of the Special Issue in the months leading up to the submission deadline and once it has been published.
What Immunology Leadership & Committees will do:
1. Immunology Leadership & Committees will circulate your Call for Papers to the Immune Editorial Board, targeted mailing lists, and relevant AoM listservs. It will also advertise your Call on the Immune websites and other social media platforms. It will re-issue the Call at appropriate intervals.
2. Once the Special Issue is published, announcements will be made to the Immune Editorial Board, targeted mailing lists, and relevant AoM listservs as well as on the Immune websites social media platforms.
3. Free access to the Special Issue will be made available in the website to Guest Editors and readers.
What is expected of Guest Editors?
1. We expect that Guest Editors will circulate the Call for Papers within their own personal networks, social media groups, and at any relevant conferences or workshops they may attend.
2. If it has not already been suggested as part of the proposal, consideration should be given to organizing a conference or workshop either to generate submissions or to aid in the development of submitted papers. A symposium or PDW at a well-known conference may also be considered.
3. We expect Guest Editors to identify up to 50 scholars for whom the Special Issue will be particularly relevant
If you have any queries, please contact Elena Griffin (editors.ijit.immune@helicsgroup.net)
EDUCATION AND TRAINING:
| UNDERGRADUATE SCHOOL | DATES (MONTH/YEAR) | DEGREE/YR/SUBJECT |
|
Guangzhou Medical College Guangzhou, P.R. China. |
09/1980-08/1985 | BA 1985, Medicine |
GRADUATE/PROFESSIONAL SCHOOL
|
Medical College of Ohio |
09/1991-06/1996 | PhD 1996, Neuroscience |
GRADUATE MEDICAL EDUCATION
| Residency,Surgery |
The Second Guangzhou Medical College Hospital Guangzhou, P.R. China |
09/1985-08/1991 |
| Residency,Pathology | North Shore Uni-Long Island Jewish Medical Ctr New Hyde Park, New York |
07/2000-06/2004 |
|
Fellowship |
Johns Hopkins Medical Institute Baltimore, Maryland |
07/2004-08/2005 |
POSTDOCTORAL EXPERIENCE
|
Medical College of Ohio |
07/1996-06/2000 |
.
ACADEMIC HONORS AND AWARDS
Graduate Dean’s Award, Ph. D in Medical Science Medical College of Ohio 1996
People Choice Award Medical College of Ohio 1996
Favorite Poster/Presentation, Research Forum,
Recognition Award, Wayne state University School of Medicine, Nephrology 2009
for significant contribution to the nephrology fellows teaching
Editorial Board Member Scholarena Journal of Case Report 2014
Editorial Board Member J. Forensic Research and Crime Studies 2014
Editorial Board Member Scholarena Journal of Infectious Diseases 2014
Editorial Board Member Bioaccent Online J. of Medical and Nurse 2015
Editorial Board Member Journal of Clinical & Medical Case Reports 2015
Editorial Board Member Pathology and Laboratory Medicine 2015
Editorial Board Member Journal of Syndromes 2015
Editorial Board Member Journal of human pathology 2015
Inspector, College of American Pathology 2013
Invited speaker Annual rheumatology conference, Temple University 2015
Invited speaker 4th International Conference and Exhibition on Pathology 2015
Invited speaker 5th World Congress on Cell Science & Stem Cell Research 2015
Invited speaker Grand round, Department of rheumatology, Temple University 2015
Editorial Board Member Madridge Journal of Vaccines 2016
Editorial Board Member SM Journal of Clinical Pathology 2016
Editorial Board Member Madridge Journal of Immunology 2016
Editorial Board Member Clinical Pathology Leaflets 2016
Editorial Board Member Pathology discipline 2016
Editorial Board Member Journal of biomarker and applications 2016
Editorial Board Member International J Pulmonary & Infectious Disease 2017
Editorial Board Member J of Laboratory Medicine 2017
Editorial Board Member Heighpubs Journal of Case Reports 2017
Editorial Board Member Clinical Nephrology and Research 2017
Editorial Board Member Clinical HIV and AIDS Journal 2017
Editorial Board Member Journal of Pathology Clinical and Medical
research 2017
Editorial Board Member Journal of Pathology Clinical and Infectious
disease 2017
Editorial Board Member Clinical and Medical case report 2017
Editorial Board Member Global Scientific Research Journal 2017
Editorial Board Member Journal of Kidney treatment and diagnosis 2017
Editorial Board Member Clinical Research and Pharmacy 2017
Editorial Board Member Clinical Pathology and Research Journal 2018
PUBLICATIONS:
PEER-REVIEWED ARTICALS
1. Zeng, X.; Xie, XH. and Tietz, EI. Impairment of feedforward inhibition in CA1 region of hippocampus after chronic benzodiazepine treatment. Neurosci. lett. 173:40-44, 1994. PMID:7936420
2. Zeng, X.; Xie, XH. and Tietz, EI. Reduction of GABA-medicated inhibitory postsynaptic potentials in hippocampus CA1 pyramidal cells following oral flurazepam administration. Neuroscience. 66:87-89, 1995. PMID: 7637878
3. Zeng, X. and Tietz, EI. Depression of both early and late monosynaptic inhibitory postsynaptic potentials in hippocampus CA1 neurons following chronic benzodiazepine treatment. Synapse. 25:125-136 1996. PMID: 9021893
4. Zeng, X. and Tietz, EI. Benzodiazepine tolerance at GABAergic synapses on hippocampal CA1 pyramidal cells. Synapse. 31: 263-277, 1999. PMID: 10051107
5. Chen S.; Huang, X.; Zeng, X.; Sieghart, W. and Tietz, EI. Benzodiazepine-mediated regulation of a1-2, ß1-3 and g2 GABAA subunit proteins in the rat brain hippocampus and cortex. Neuroscience 93:33-44, 1999. (study conception, design, implementation, data analysis). PMID: 10430468
6. Zeng, X. and Tietz, EI. Role of bicarbonate in mediating conductance in benzodiazepine tolerant hippocampal CA1 pyramidal cells. Brain Research. 868: 202-241, 2000. PMID: 10854572
7. Tietz, EI.; Zeng, X.; Chen S. Lilly, S.; Rosenberg, H.C. and Kometiani, P Antagonist-induced reversal of functional and structural measures of hippocampal BZ tolerance. J Phamacol Exp. Ther. 291: 932-935 1999. (study conception, design, implementatio, data analysis). PMID:10565808
8. Tietz, EI.; Shanyi C.; Zeng, X. and Sieghart, W. Role of protein kinase A in GABAA receptor dysfunction in CA1 pyramidal cells following chronic benzodiazepine treatment. J Neurochem. 85(4):988-98 2003. PMID:12716430
9. Zeng, X.; El-Amm, J.M.; Doshi, M.D.; Singh, A.; Morawski, K.; Cincotta, E.; Losanoff, J.E.; West, M.S.; Gruber, S.A. Intermediate-term outcomes with early steroid withdrawal in African- American renal transplant recipients undergoing surveillance biopsy. Surgery, 142(4): 538-545 2007. PMID: 17950346
10. Franco C, Yoo W, Zeng X. Lupus nephritis in an African American Population. The International Journal of Medicine ISSN 1360-0168, March 2009 (study conception, design, implementation, data analysis).
11. Franco C, Yoo W, Franco D, Zeng X. Predictors of end stage renal disease in African American with lupus nephritis. Bulletin of the NYU Hospital for Joint disease. 68 (4): 251-256, 2010 (study conception, design, implementation, data analysis). PMID: 21162701
12. Liu Xianbao, Zhan Hong, Xu Zeng, Zhang Chunfang and Chen Dunjin. The PBDE 209 exposure during pregnancy and lactation impairs immune function in rats. Mediators of Inflammation. Accepted 02/01/2012
13. Liu, Xianbao, Zhan, Hong, Zeng, Xu, Zhang Chunfang, Chen Dunjin Dexmedetomidine reduced cytokines release in postpartum bleeding-induced multiple organs dysfunction syndrome rat. Submitted to Journal of Anesthesiology at April 01, 2013.
14. Bhat ZY, Bostwick DG, Hossain D, Zeng, X Participation of functionally active plasma cells in acute rejection and response to therapy in renal allografts. DNA and Cell Biology 33 (7): 1-7 2014.
15. Gonzalez-Suarez M1, Waheed A, Andrews D, Ascherman D, Zeng X, Nayer A. Lupus vasculopathy: Diagnostic, pathogenetic and therapeutic considerations. Lupus. 2014; 23(4):421-7. PMID: 24452079
16. Zeng, X; Adabala, M; Bostwick, DG; Hossain, D and Mattoo T. Henoch-Scholein purpura nephritis in Children: A severe IgA nephropathy. Scholarena Case report. 2014; 1(2):201-8.
17. Zeng, X. Hossain, D; Bostwick, D. Herrera, G; Ballester B. and Zhang, PL; Urinary β2-microglobulin is a sensitive indicator for renal tubular injury. Scholarena Case report. 2014; 1(1):103-8.
18. Ojemakinde K, Turbat-Herrera EA, Zeng X, Gu X and Herrera GA; The many faces of cryoglobulinemic nephropathy: A clinic-plthologic study of 43 cases with emphasis on the value of electron microscopy. Ultrastructural Pathology: 38 (6): 367-76. 2014
19. Herrera GA, Ojemakinde K, Turbat-Herrera EA, Gu X, Zeng X and Iskandar SS; Immunotactoid glomeruopathy and cryoglobulinemic nephropathy: two entities with many similarities. A unified conceptual. Ultrastructural Pathology: 39 (4): 270-80. 2015
20. Zeng, X. Hossain, D; Bostwick, D. Herrera and Zhang, PL; Urinary β2-microglobulin is a good indicator for renal proximal tubular injury: a correlative study with renal biopsies. J. biomarkers 2014; Vol. 2014: 1-7 (Article ID 492838).
21. Cosner D, Zeng, X. and Zhang, PL; Proximal tubular injury in medullary rays is a first sign of acute tacrolimus nephrotoxicity. J. of Transplantation. 2014 (Article ID 142521)
22. Eskandari M, Zeng, X. and Zhang, PL; Kidney injury molecule-1 is a sensitive and specific marker of acute tubular injury in pediatric renal biopsy. J Transplantation. 2014
23. Rao S,Ghanta M, Lee, IJ, Gillespie, A, Parekh, H, Geier, SS, Zeng X, Karachristos, A, Lau, KN, Karhadkar, s, Carlo, AD, Sifontis, N and Constantinescu, S. Impact of HLA antibody monitoring and Kidney Transplantation. Clinical Transplant 2014 chapter 18:143-151
24. Devasahayam J, Ero-Singaravelu G, Bhat Z, Oliver T, Chandran A, Zeng X, Dakshinesh P and Pillai U: C1q nephropathy: the unique under recognized pathological Entity. Analytical Cellular Pathology Vol. 2015 (Article ID 490413)
25. Chen J, Lan Q, Jin S, Zeng X and Zhan H: Administration of Vasoconstrictor, but not Volume Expander Prevents Maternal Hypotension during Spinal-Epidural Anesthesia for Elective Cesarean Section. Scholarena Case report. 2016; 3(1):102-111.
26. Malik A, Benjamin J and Zeng X: Nephropathy associated with prolong lithium administration. Scholarena Case report. 2016; 3(1):
27. Menon S, Zeng X, Valentini R. Fibrillary glomerulonephritis and renal failure in a child with systemic lupus erythematosus. Pediatr Nephrol. 2009 Mar 24. PMID:19308460
28. Jung K, Zeng. X and Bilusic M. Nivolumab-assoicated acute glomerulonephritis: a case report and literature review. BioMed Central Nephrology. 2016
29. Zeenat B, Zeng X, Jaideep H, Madhumita JM. Fibrillary Glomerulonephritis in a patient with Systemic Lupus Erythematosus -a rare association (International Urology and Nephrology; e-published on 11/19/2011, PMID: 22102086
30. Sendzischew MA, Vieregge GB, Contreras G. Zeng X, Nayer A. Plasma exchange for Lupus Nephritis and Antiphospholipid Syndrome. Clinical Kidney Journal, 7 (1): 86-89 2013.
31. Qadri, I; Zeng, X; Guo, R; Koratala, A. Acute Interstitial Nephritis and DRESS Syndrome without Eosinophilia associated with Cefepime. BMJ Case report 2017: 3 August 2017.
32. Koratala, A; Malpartida, F; Zeng, X. Emphysematous pyelonephritis. Clinical Case Report. 2017, 2018; 6(2): 439–441, Article ID: CCR31364/DOI: 10.1002/CCR3.1364.
33. Koratala, A; Zeng, X; Tantravahi, J. Nephrotic syndrome in very elderly: should we treat aggressively? Clinical Case Report. 2017.
34. Koratala, A; Zeng, X. Rituximab Therapy for Hepatitis C virus Associated Cryoglobulinemic Membranoproliferative Glomerulonephritis. Clinical Case Report. 2018; 6(2): 442–443, Article ID: CCR31371/DOI: 10.1002/CCR3.1371.
35. Koratala, A; Zeng, X; Kazory, A. ANCA positive IgA nephropathy without necrotizing or crescentic glomerulonephritis: a clinical conundrum. BMJ Case Reports. 11/13/2017 accepted, Article ID: BCR-2017-222171/DOI: 10.1136/BCR-2017-222171.
36. Koratala, A; Khan, Roohan; Zeng, X. Silent acute interstitial nephritis: Suspicion is the key to diagnosis. American J. of medicine. April 2018.
37. Kamboj, M; Zeng, X; Koratala, A. Renal cyst infection: a diagnostic dilemma. Clinical Case Report. Accepted 01/31/2018.
38. Chamarthi, G; Kamboj, M; Olaoye, O; Zeng, X; Koratala, A. Acute Interstitial Nephritis: A multifaceted Disease. Clinical Case Report. Accepted 02/09/2018.
Case Reports in preparation:
1. Kulkarni T, Zeng X, Karia VR. Successful induction of remission of severe Wegener’s Granulomatosis: A case report. Journal of Clinical Rheumatology (submitted)
2. Karia V, Zeng X, A rare cause of hemoptysis and renal failure in an African-American male. (submitted)
3. De Prada, LK and Zeng X. Anti-Glomerular Basement Membrane disease and Anti-Neutrophil Cytoplasmic Antibodies Associated with Cocaine use: A case report (submitted to America Journal of Kidney Disease)
4. Singh A, Zeng X, Rossi, N. Unusual presentation of drug induced collapsing focal segmental glomerulosclerosis
5. Greist H, Hingorani J, Zeng X, Mehta K, Singh A, Dhar P. Pauci-immune glomerulonephritis in a patient with systemic lupus erythematosus
Book Chapters, Review Articles, Other Non-Refereed
Zhou XJ, Zeng X, Diagnostic Renal Pathology, Chapter 6 Crescentic Glomerulonephritis (in Chinese).
Rogers TJ, Zeng X, Wang, H, Essentials of Clinical Pulmonology, Chapter: Chronic obstructive pulmonary disease.
PUBLISHED ABSTRACTS
